Urea (carbamide) — chemical compound, diamide of carbonic acid. White crystals, soluble in polar solvents (water, ethanol, luquid ammonia).
Urea is discovered by Ruehl in 1773 and identified by Praut in 1818. Special significance to urea in the history of organic chemistry was attached by the fact of its synthesis from inorganic matters by Vyoler in 1828 :
This transformation is the first synthesis of organic compound from inorganic. Vyoler received urea heating of the ammonium cyanate received by in situ interaction of potassium cyanate with ammonium sulfate. This event struck the first blow to vitalism — to the doctrine about vital force.