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Apramitsina sulfate

Apramitsina sulfate

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  • Country of manufactureBulgaria

Apramitsina sulfate, art.258088679

Powder loose, fine, from light yellow till light brown color, soluble in water.

Antibiotic of veterinary appointment from group of aminoglycosides. The preparation has bactericidal effect mainly concerning gramotritsatelny, and also some grampolozhitelny bacteria, including Escherichia coli, Salmonella spp., Pseudomonas spp., Staphylococcus spp., Streptococcus spp., Proteus spp., Bordetella bronchiseptica, Klebsiella spp., Shigella spp., Campylobacter spp., Brachyspira hyodysenteriae and some types of mycoplasmas (Mycoplasma hyopneumoniae).

It is not active concerning anaerobic microorganisms.

The mechanism of antibacterial action of an apramitsin is caused by suppression of synthesis of protein of microorganisms by irreversible linkng with a 30S-subjedinitsa of ribosomes.

At oral introduction Apramitsin water-soluble powder is poorly soaked up and reaches high antibacterial concentration in a gastrointestinal tract. Apramitsin is not exposed to biotransformation in an organism of animals and after oral introduction is brought in not changed active look, mainly with a stake and partially? with urine.

In the recommended doses does not render embriotoksichesky, teratogenny, mestnorazdrazhayushchy and allergiziruyushchy action.

Apramitsin water-soluble powder on extent of impact on an organism treats low-dangerous substances (the 4th class of danger in accordance with GOST 12.1.001-76).

Indications to application of preparation APRAMITSIN WATER-SOLUBLE POWDER

Treatment of the gastrointestinal diseases caused by sensitive microorganisms at farm animals (including at calfs, pigs, lambs and chickens):

— gastroenterokolita of pigs, sheep and a bird salmonellezny, kolibakteriozny, pseudo-monoheat and a kokkovy etiology -

— kolibakterioz broilers and repair young growth kur-nesushek-

— toxic dyspepsia of calfs.

Application order

Apramitsin water-soluble powder is appointed an animal inside with drinking water, and to calfs and lambs? with milk or the substitute of whole milk (SWM) of 1 times/days within 5-7 days in the following doses:

Species of animals Apramitsin's dose
water-soluble powder
Pigs 15-25 mg/kg of body weight
Calfs 40-80 mg/kg of body weight
Lambs 20 mg/kg of body weight
Repair young growth of laying hens, broilers 50-100 mg/kg of live weight or 0.5-1 g/l of water

Before application the single dose of Apramitsin of water-soluble powder should be dissolved in the 5-10-fold volume of liquid (water, milk or ZTsM), adding it to powder, after that to allow solution to be defended several minutes, again to mix and bring volume to necessary final concentration.

At Apramipin's use of water-soluble powder with drinking water (for broilers, repair young growth of laying hens) the calculated dose of an antibiotic is recommended to be mixed and a half the daily volume of the consumed water. Since ions of iron reduce activity of an antibiotic, solution of a preparation cannot be prepared in rusty metal capacities.

Ready water solution of Apramitsin of water-soluble powder has to be used within 3 days, and solution on milk or ZTsM? within a day after preparation.

Side effects Data on side effect of a preparation are not provided. Characteristics
Main attributes
Country producer Bulgaria
The producer - Import
Dosage form Powder
Additional characteristics
Packing 10 kg
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